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Deep Neuromuscular Blockade on Postoperative Pain
Sponsor: Seoul National University Hospital
Summary
This study aims to investigate the impact of varying degrees of neuromuscular blockade on postoperative pain in pediatric patients aged over 2 months to under 7 years undergoing laparoscopic surgery under general anesthesia.
Official title: Effect of Deep Neuromuscular Blockade on Postoperative Pain in Pediatric Patients Undergoing Laparoscopic Surgery: a Prospective Randomized Controlled Trial
Key Details
Gender
All
Age Range
2 Months - 7 Years
Study Type
INTERVENTIONAL
Enrollment
106
Start Date
2024-11-06
Completion Date
2026-11-07
Last Updated
2025-05-13
Healthy Volunteers
No
Conditions
Interventions
rocuronium 0.2 mg/kg/hr continuous infusion
To maintain Train-of-four count 1 to 3 during surgery: Administration of continuous infusion of rocuronium at a rate of 0.2 mg/kg/hr to achieve and sustain moderate neuromuscular blockade.
rocuronium 0.6 mg/kg/hr continuous infusion
To maintain Train-of-four count 0 during surgery: Administration of continuous infusion of rocuronium at a rate of 0.6 mg/kg/hr to achieve and sustain deep neuromuscular blockade.
Locations (1)
SNUCH
Seoul, Seoul, South Korea