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Silver Nitrate vs. Triamcinolone for Treatment of Hypergranulation Tissue
Sponsor: Francesco Egro
Summary
This randomized controlled trial aims to compare the efficacy of silver nitrate, triamcinolone, and a successive use of both treatments in managing hypergranulation tissue in traumatic wounds. Conducted over a four-year period at UPMC Mercy, the study will involve patients presenting with hypergranulation tissue. Participants will be randomly assigned to receive either topical silver nitrate, topical triamcinolone, or a combination of the two in succession. The study will assess treatment outcomes based on the reduction or resolution of hypergranulation tissue, with the goal of identifying the most effective therapeutic approach. This research will provide valuable insights into optimizing treatment strategies for hypergranulation tissue in traumatic wounds.
Official title: A Comparative Study of Silver Nitrate, Triamcinolone, and Their Successive Combined Use on Hypergranulation Tissue in Traumatic Wounds: A Randomized Control Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
270
Start Date
2025-06-01
Completion Date
2028-12-31
Last Updated
2025-03-10
Healthy Volunteers
No
Conditions
Interventions
Silver Nitrate
See "Silver nitrate only" study arm
triamcinolone
See "Triamcinolone only" study arm
Silver nitrate + triamcinolone
See "Combination group" study arm
Locations (1)
UPMC Mercy Hospital
Pittsburgh, Pennsylvania, United States