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NOT YET RECRUITING
NCT06681194
PHASE2/PHASE3

Silver Nitrate vs. Triamcinolone for Treatment of Hypergranulation Tissue

Sponsor: Francesco Egro

View on ClinicalTrials.gov

Summary

This randomized controlled trial aims to compare the efficacy of silver nitrate, triamcinolone, and a successive use of both treatments in managing hypergranulation tissue in traumatic wounds. Conducted over a four-year period at UPMC Mercy, the study will involve patients presenting with hypergranulation tissue. Participants will be randomly assigned to receive either topical silver nitrate, topical triamcinolone, or a combination of the two in succession. The study will assess treatment outcomes based on the reduction or resolution of hypergranulation tissue, with the goal of identifying the most effective therapeutic approach. This research will provide valuable insights into optimizing treatment strategies for hypergranulation tissue in traumatic wounds.

Official title: A Comparative Study of Silver Nitrate, Triamcinolone, and Their Successive Combined Use on Hypergranulation Tissue in Traumatic Wounds: A Randomized Control Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

270

Start Date

2025-06-01

Completion Date

2028-12-31

Last Updated

2025-03-10

Healthy Volunteers

No

Interventions

DRUG

Silver Nitrate

See "Silver nitrate only" study arm

DRUG

triamcinolone

See "Triamcinolone only" study arm

DRUG

Silver nitrate + triamcinolone

See "Combination group" study arm

Locations (1)

UPMC Mercy Hospital

Pittsburgh, Pennsylvania, United States