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RECRUITING
NCT06682325

Pharmaco-proteomic Platform to Evaluate Drug Interactions in Liver Transplant Patients

Sponsor: Pontificia Universidad Catolica de Chile

View on ClinicalTrials.gov

Summary

The goal of this observational study is to enhance the ability to forecast kidney failure in liver transplant patients in the ICU under multidrug treatment by developing a computer platform that integrates mathematical models of drug interactions, proteomics, and clinical data. The main outcomes it aims to develop are: 1. Design the multidrug web computing platform with available information on drug pair interactions (DDIs). 2. Integrate the proteomic and clinical data of liver transplant patients into the IT platform. 3. Implement the multidrug web platform to predict the clinical evolution of liver transplant patients.

Official title: Development of a Pharmaco-proteomic Platform to Evaluate Potential Drug Interactions and Their Clinical Impact in Liver Transplant Patients Undergoing Multidrug Treatment

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

48

Start Date

2023-06-01

Completion Date

2025-05-05

Last Updated

2024-11-12

Healthy Volunteers

No

Interventions

OTHER

Multi-drug interaction

The clinical impact associated with the use of multiple drugs in liver transplant patients during their stay in ICU will be evaluated.

Locations (3)

Universidad de Valparaíso

Valparaíso, Región de Valparaíso, Chile

Hospital ClínicoUC-Christus

Santiago, Santiago Metropolitan, Chile

Pontificia Universidad Católica de Chile

Santiago, Santiago Metropolitan, Chile