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Beta-Cell - Liver Interactions in Situations of Modified Beta-Cell Function
Sponsor: Philippe Klee, MD-PhD
Summary
The investigators will measure blood levels of 1,5-anhydroglucitol in obese children with or without type 2 diabetes and correlate them with parameters related to functional beta-cell mass and glucose metabolism. The values will be compared to those obtained in healthy volunteers. The aim of the study is to test the validity of 1,5-anhydroglucitol as a novel biomarker of beta-cell mass and function in children with obesity with or without type 2 diabetes.
Official title: Beta-Cell - Liver Interactions in Situations of Modified Beta-Cell Function: From Mice to Children
Key Details
Gender
All
Age Range
12 Years - 16 Years
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2024-11-22
Completion Date
2028-12-31
Last Updated
2025-04-02
Healthy Volunteers
No
Interventions
Measurement of biomarker
Measurement of blood levels of 1,5-anhydroglucitol
Locations (1)
University Hospital of Geneva
Geneva, Canton of Geneva, Switzerland