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RECRUITING
NCT06682481

Beta-Cell - Liver Interactions in Situations of Modified Beta-Cell Function

Sponsor: Philippe Klee, MD-PhD

View on ClinicalTrials.gov

Summary

The investigators will measure blood levels of 1,5-anhydroglucitol in obese children with or without type 2 diabetes and correlate them with parameters related to functional beta-cell mass and glucose metabolism. The values will be compared to those obtained in healthy volunteers. The aim of the study is to test the validity of 1,5-anhydroglucitol as a novel biomarker of beta-cell mass and function in children with obesity with or without type 2 diabetes.

Official title: Beta-Cell - Liver Interactions in Situations of Modified Beta-Cell Function: From Mice to Children

Key Details

Gender

All

Age Range

12 Years - 16 Years

Study Type

OBSERVATIONAL

Enrollment

50

Start Date

2024-11-22

Completion Date

2028-12-31

Last Updated

2025-04-02

Healthy Volunteers

No

Interventions

OTHER

Measurement of biomarker

Measurement of blood levels of 1,5-anhydroglucitol

Locations (1)

University Hospital of Geneva

Geneva, Canton of Geneva, Switzerland