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Real-life Evaluation of the Efficacy of Biologicals in Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)
Sponsor: Universitaire Ziekenhuizen KU Leuven
Summary
The goal of this observational study is to learn more about the real-world efficacy of biologics in patients with chronic rhinosinusitis with nasal polyposis (CRSwNP). All patients who are 18 years or older, who have CRSwNP and are eligible for reimbursement of a biological for the indication of CRSwNP can be included. The main question is the efficacy of biologics in real life after 24 weeks. The main focus are patient reported outcomes measured via several questionnaires and the nasal polyp score, scored with nasal endoscopy.
Official title: Real-life Evaluation of the Efficacy of Biologicals in CRSwNP
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2022-09-23
Completion Date
2026-12
Last Updated
2024-11-12
Healthy Volunteers
No
Interventions
Omalizumab
biological prescribed as add-on treatment as part of the standard of care
Dupilumab
biological prescribed as add-on treatment as part of the standard of care
Mepolizumab 100 mg
biological prescribed as add-on treatment as part of the standard of care
Locations (8)
Onze Lieve Vrouw hospital Aalst
Aalst, Belgium
General hospital Sint-Jan Bruges
Bruges, Belgium
University hospital Saint-Luc
Brussels, Belgium
University hospital of Antwerp
Edegem, Belgium
Hospital Zuid-Oost Limburg
Genk, Belgium
University Hospital Brussels
Jette, Belgium
University hospitals Leuven
Leuven, Belgium
CHU de Liège
Liège, Belgium