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Convergent Mechanisms Underlying Reprometabolic Syndrome in Women
Sponsor: University of Colorado, Denver
Summary
Dr. Nanette Santoro proposes to test the specific question that obesity results in abnormal estradiol response at the level of the pituitary and hypothalamus. This will be shown in diminished pituitary sensitivity to gonadorelin releasing hormone with a reduced estradiol induced luteinizing hormone surge in obese women.
Official title: Convergent Mechanisms Underlying Reprometabolic Syndrome in Women and Sheep
Key Details
Gender
FEMALE
Age Range
18 Years - 38 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2025-02-25
Completion Date
2026-12
Last Updated
2025-05-01
Healthy Volunteers
Yes
Conditions
Interventions
Estradiol Patches
Estradiol patched will be worn for 7 days.
Locations (2)
University of Colorado School of Medicine
Aurora, Colorado, United States
University of Colorado-School of Medicine
Aurora, Colorado, United States