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RECRUITING
NCT06689111
NA

Correlation of Typical LBBB Mechanical Activation Pattern by 2D Strain Echocardiography With Acute GWE Improvement in Patients Receiving LBBp or Conventional BiVp for Cardiac Resynchronization Therapy (Echo LBBp)

Sponsor: University Hospital of Patras

View on ClinicalTrials.gov

Summary

The present study is a multicenter interventional non randomised study in patients requiring an implantable device for cardiac resynchronization therapy. Its primary objective is to investigate whether the presence of a specific echocardiographic contraction pattern before implantation is associated with increased rates of acute improvement in myocardial function (as measured by an ultrasound) and to compare the improvement in two groups of patients based on the type of pacing (biventricular or left-sided pacing)

Official title: Investigation of Whether the Presence of the Typical LBBB- Mechanical Stimulation Pattern - Documented Through 2DSE (Two-dimensional Strain Echocardiography) - is Associated With Increased Rates of Acute Improvement in Global Myocardial Work Efficiency (GWE) Compared to the Absence of This Activation Pattern, in Patients in Need of Device Implantation for Cardiac Resynchronization Therapy in Whom LBBp is Chosen Compared to the Classic Biventricular Pacing Method

Key Details

Gender

All

Age Range

18 Years - 90 Years

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2024-05-23

Completion Date

2026-11-30

Last Updated

2025-12-05

Healthy Volunteers

No

Interventions

DEVICE

Left bundle branch pacing lead

Use of LBBp Vs the standard method of BiVp in resynchronization therapy

DEVICE

CRT with the standard method through cs

standard CRT procedure

Locations (1)

University Hospital of Patras

Pátrai, Greece, Greece