Clinical Research Directory

Inclusion Criteria: 1. Adult age over 18 years. 2. Arm circumference is 18 cm to 55 cm 3. Subject will have an existing indwelling central venous catheter during their ICU stay 4. Subject or legally authorized representative (LAR) is able to understand the risks and potential benefits of participating in the study and is willing to provide written informed consent 5. Subject or LAR is willing and able to comply with protocol procedures Exclusion Criteria: 1. Finger and/or upper arm anatomical anomaly or disease that may interfere with attaching a pulse oximeter sensor and/or blood pressure cuff. 2. Pregnant (self-reported) 3. Upper extremity deep venous thrombosis currently being treated 4. Severe skin disease involving the upper arm(s) 5. Study investigator may exclude patients based on clinical judgement