Clinical Research Directory

Inclusion criteria for sporadic ICA cases: * Any adult patient consulting for a definite and typical bifurcation AIC authenticated on MRI and/or cerebral arteriography * Aneurysm discovered less than a year ago, with initial imaging (MRI and/or CTA and DSA) available * Written consent obtained for study participation * Patient covered by a social security plan Inclusion criteria for index and related cases (familial forms) of intracranial aneurysms (ICA): * Index case: Any adult patient consulting for a definite and typical bifurcation ICA presenting at least one other case with ICA related to the 1st or 2nd degree (child, parent, brother, sister) detected by MRI with at least one Time of Flight (TOF) sequence. * Family relatives: All 1st- and 2nd-degree relatives (children, parents, brothers, sisters), of legal age, of patients with a family history of definite, typical bifurcation AIC (≥ 2 affected), Screening to be performed using MRI with at least a Time of Flight (TOF) sequence. * Written consent to participate in the study * Patient and relatives covered by a social security plan Exclusion Criteria: * Syndromic diagnosis known to cause ICA: Marfan syndrome, OSA with SMAD 3, Elhers Danlos syndrome type II and IV, Autosomal Dominant Cystic Fibrosis, Moya-Moya syndrome * AIC with : Dissecting or fusiform, Associated with arteriovenous malformation, Blister-like, Mycotic * Cerebral white matter pathology detected on MRI evoking : Col4a1 mutation * Patient under guardianship or conservatorship * Person under court protection * Contraindication to an MRI scan