Clinical Research Directory

Inclusion Criteria: 1. Infant 6-11 weeks of age. 2. Infant born after 37-42 weeks of pregnancy. 3. Infant weighing more than 2.5 kg at birth. 4. Father or mother, or legally acceptable representative properly informed about the study and signed the informed consent form. 5. Parents will commit themselves to comply with the indications of the investigators and with the schedule of the trial. Exclusion Criteria: 1. Child concomitantly enrolled or scheduled to be enrolled in another trial. 2. Evolving moderate or severe illness, especially infectious diseases or fever (axillary temperature ≥37.5°C on Day 0). 3. Known history of allergy to any component of the vaccines. 4. History of uncontrolled coagulopathy or blood disorders contraindicating intramuscular injection. 5. Known history of congenital or acquired immunodeficiency (including HIV infection). 6. Child who has received in the previous 4 weeks of a treatment likely to alter the immune response (intravenous immunoglobulins, blood-derived products or long term corticotherapy (\> 2 weeks). 7. Other vaccination within the 7 days prior to inclusion with the exception of BCG and poliomyelitis. 8. Any abnormality or chronic disease which according to the investigator might interfere with the assessment of the trial objectives. 9. Infant with a known history of diphtheria, tetanus, pertussis, Hib, hepatitis B infection.