Clinical Research Directory
Browse clinical research sites, groups, and studies.
Physiological Effects of Lung Impedance Tomography-Guided and Plat Pressure-Guided Phigh During APRV in Patients With ARDS
Sponsor: XiaoJing Zou,MD
Summary
This study aims to investigate the effects of EIT-guided and Pplat-guided Phigh settings on regional ventilation and perfusion in ARDS patients during APRV, while also examining the impact of different Phigh settings on gas exchange, respiratory mechanics, and hemodynamics.
Official title: Physiological Effects of Lung Impedance Tomography-guided and Plat Pressure-guided Phigh During Airway Pressure Release Ventilation in Patients With Acute Respiratory Distress Syndrome
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
26
Start Date
2025-01-01
Completion Date
2026-12-31
Last Updated
2025-01-06
Healthy Volunteers
No
Interventions
EIT-guided Phigh settings during APRV
The Phigh level selected for the patients in the Intervention group was the intercept point of cumulated collapse and overdistension percentage curves, providing the best compromise between collapsed and overdistended lung.
Locations (1)
Wuhan Union hospital
Wuhan, Hubei, China