Clinical Research Directory

For SCI participants: Inclusion Criteria: * At least 18 years of age * Non-progressive cervical SCI * Greater than or equal to 6-months post spinal cord injury * Stable medical condition * Viable median and ulnar nerve as evident from MMR and M-Wave recordings * Wrist extensor and finger flexors score between 1-3 for both upper extremity for ISNCSCI motor assessment. Exclusion Criteria: * Ventilator Dependent * Untreated fracture or pressure ulcer * Untreated psychiatric disorder or ongoing drug abuse * Cardiac, respiratory, bladder, renal, or other untreated medical disorder unrelated to SCI * Skeletal muscle Botox injections less than 6 months prior * Previous tendon transfer of the arm or arms * Any implanted pump (i.e., baclofen pump, pain pump, etc.) prior to randomization * Pregnant at the time of enrollment or planning to become pregnant during the course of the study * Unable or unwilling to wean from anti-spasticity medications * History of seizure or epilepsy * Metal in Head * Cochlear implant * Implanted brain stimulators * Aneurysm clips * Increased intracranial pressure (which lowers seizure threshold) * Cardiac pacemaker * Personal or family history of epilepsy * Tricyclic antidepressants or neuroleptics (which lower seizure threshold) For healthy volunteer/participants: Inclusion Criteria: * At least 18 years of age Exclusion Criteria: * Neurological injury or disease * Pregnant at the time of enrollment or planning to become pregnant during the course of the study * Personal or family history of seizure or epilepsy * Tricyclic antidepressants or neuroleptics (which lower seizure threshold)