Clinical Research Directory

Inclusion Criteria: * Adults between 18 and 80 years of age. * Requirement for single-rooted tooth extraction due to reasons such as caries, fractures, restorative issues, endodontic complications (e.g., root fracture, instrument fracture), orthodontic needs, or prosthetic considerations. * Presence of at least one neighboring tooth adjacent to the extraction site. * Maintaining adequate oral hygiene, indicated by bleeding on probing \<20% and plaque index \<20%. * Presence of at least 50% of the buccal bone plate. * Classification of patients as ASA I or II status according to the American Society of Anesthesiologists Classification. Exclusion Criteria: * All smokers, including smoking alternatives. * Heavy drinker (\> 60 g of alcohol per day as a mean). * Uncontrolled metabolic disorders e.g., diabetes mellitus, osteomalacia, thyroid disorder, severe renal or hepatic disorder. * Prolonged corticosteroid therapy. * Immunological impairment diseases. * History of malignancy, radiotherapy, or chemotherapy for malignancy within the past five years. * General contraindications for dental and/or surgical treatment (including patients who take anticoagulants or antiresorptives). * Disease or condition affecting bone metabolism. * Women of child-bearing age, not using a highly effective method of birth control. * Pregnancy or breast feeding. * Previous and concurrent medication affecting sinus healing in general (e.g., topical steroids, large doses of anti-inflammatory drugs). * Acute or chronic oral infection or uncontrolled periodontal disease. * Crestal bone defects at the implantation site, which require additional bone augmentation around the neck of the implant. * Allergy to collagen. * Participation in an investigational device or drug clinical trial within the last six month.