Clinical Research Directory

Inclusion Criteria: 1. No gender limit, age ≥ 18 years； 2. Acute non-hematochezia gastrointestinal bleeding symptoms, including haematemesis or melena； 3. Taking antiplatelet drugs continuously for at least 14 days； 4. Hemodynamically stable； 5. Able to provide informed consent. Exclusion Criteria: 1. Age \< 18 years； 2. Hemodynamically unstable even after initial volume resuscitation and/or have ongoing fresh hematemesis at presentation； 3. With upper gastrointestinal bleeding caused by peptic ulcer or acute gastric mucosal lesion within 1 month before inclusion； 4. History of endoscopic therapy (such as ESD, EMR, etc.) within 1 month before inclusion； 5. Gastrointestinal tumor, decompensation of cirrhosis with esophageal or gastric varices； 6. Haematopathy and bleeding tendency； 7. Patients who have no surgical conditions or refuse to undergo any abdominal surgery (once the capsule is stuck, it cannot be removed surgically)； 8. Pacemaker or other implanted electromedical devices which could interfere with magnetic resonance； 9. Patients plan to undergo magnetic resonance imaging examination before excretion of the capsule； 10. Suspected or known intestinal stenosis or other known risk factors for capsule retention. 11. Pregnancy； 12. Dysphagia； 13. With and conditon contraindicated to ds-MCE or EGD； 14. With and conditon that is not suitable for participation in the study evaluated by researchers.