Clinical Research Directory

Inclusion Criteria: * Adult Participants aged 16 years old and above. * Healthy growing Participants without any systemic diseases (assessed by taking a brief medical history ). * Participants with skeletal Class I relationship. * Participants with any other dental malocclusion referring to the Index of Orthodontic Treatment Need Index of orthodontic treatment needed (IOTN) . * No active extensive caries and with healthy periodontal tissues. Exclusion Criteria: * Participants with any craniofacial anomalies, mental disabilities and/or neuropathic conditions. * Participants with history of neuromuscular disease and/ or truma. * Participants with the Presence of skeletal and/or diagnosed muscular asymmetries. * Participants with History of any previous orthodontic treatment. * Participants who have any signs of bruxism. * Participants with history of use of muscle relaxants. * Participants with true crossbites and/or with signs of Temporomandibular disorders (TMD) or condylar problems. * Participants with skeletal CL II and/or CL III relationships. * Participants with Hypodontia and/or with multiple missing posterior teeth (4 teeth and more). * Participants with maxillary constriction and posterior cross-bite (unilateral or bilateral) with an indication for orthognathic surgery. * Participants indicated for extraction orthodontic treatment.