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Accuracy of PoCT to ELISA by Detecting Human IL-6 in Teeth with Apical Periodontitis
Sponsor: Manipal University College Malaysia
Summary
To compare the diagnostic agreement of human IL-6 chairside PoCT to ELISA in apical periodontitis undergoing endodontic therapy which could be clinically helpful to monitor the healing of periapical tissues enabling the clinician to complete the endodontic procedure, leading to a better patient care. This study will be conducted at the Conservative and Endodontics Department in Polyclinic B, Faculty of Dentistry, Manipal University College Malaysia (MUCM). It involves 30 selected patients who have single rooted tooth with apical periodontitis that undergo RCT. The collection of the exudate from the canal will be on pre and post-instrumentation. The exudated will collect twice in each instrumentation for PoCT and ELISA.
Official title: Diagnostic Agreement of Human Interleukin-6 Chairside Point-of-Care Test (PoCT) to Enzyme-Linked Immunosorbent Assay (ELISA) in Teeth with Apical Periodontitis
Key Details
Gender
All
Age Range
17 Years - 65 Years
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2024-12
Completion Date
2025-11
Last Updated
2024-11-22
Healthy Volunteers
No
Conditions
Interventions
Point of Care Test
PoCT as a chairside test, ELISA as a gold standard
Locations (1)
Manipal University College Malaysia
Malacca, Melaka, Malaysia