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NCT06702527

Optimizing Clinical Outcomes in Patients Undergoing Mitral Transcatheter Edge-to-edge Repair (M-TEER) for Severe Functional Mitral Regurgitation Towards Improved Guideline-directed Medical Therapy

Sponsor: Institut für Pharmakologie und Präventive Medizin

View on ClinicalTrials.gov

Summary

A multi-centre, prospective, observational pilot registry in patients undergoing mitral valve repair for severe functional mitral regurgitation to report the heart failure drug therapy and dosing before the mitral valve procedure and afterwards to assess whether the recommended maximal dose of medication is administered. This maximal dose, although recommended, might not be tolerated well by patients and can cause side-effects. Researchers will determine whether the mitral valve repair procedure might have a possible effect on increasing the drug therapy towards the recommended optimal doses.

Official title: Optimizing Clinical Outcomes in Patients Undergoing M-TEER for Severe Functional Mitral Regurgitation Towards Improved Guideline-directed Medical Therapy - The MOTOR Registry

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

100

Start Date

2025-06-01

Completion Date

2026-09-01

Last Updated

2025-05-23

Healthy Volunteers

No

Interventions

PROCEDURE

Mitral transcatheter edge-to-edge repair

Mitral transcatheter edge-to-edge repair with the PASCAL system

Locations (1)

Cellitinnen Hospital St. Vinzenz

Cologne, North Rhine-Westphalia, Germany