Clinical Research Directory

Inclusion Criteria: • All patients age 18 years and older who present to Gonda 2 procedural area for Endoscopic ultrasound (EUS) with or without endoscopy (EGD)/biopsy/tissue sampling. with BMI ≥ 35 kg/m2 (BMI within the past 6 months in electronic medical records or at current procedure) who are able to consent will be approached for potential enrollment. Exclusion Criteria: * Need for general anesthesia for the procedure instead of the standard monitored anesthesia care. * Patients undergoing combined procedure: Therapeutic EUS/combined procedures including EUS/ERCP, EUS/colonoscopy * Patients on home oxygen therapy, or the diagnosis of "severe COPD" * Patients with existing tracheostomy * Inpatients undergoing EUS * Inability to consent * Cognitive impairment * Blocked nasal passages * Trauma/previous surgery to the nasopharynx * Irregularities of the nose, face, or airway such that HFNC cannot be properly fitted