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NOT YET RECRUITING
NCT06709157

Immunocompetent Versus Immunocompromised Tuberculosis (TB) Patients

Sponsor: Sohag University

View on ClinicalTrials.gov

Summary

Tuberculosis (TB) is caused by Mycobacterium tuberculosis and is one of the top 10 causes of mortality worldwide. It is estimated that in 2017, 10 million people were infected with TB, and 1.6 million died from the disease, including 0.3 million people with human immunodeficiency virus (HIV) infection . TB remains the primary killer of HIV-positive individuals. TB incidence is falling at about 2% per year . Airborne transmission of M. tuberculosis typically causes TB infection in both immunocompetent and immunocompromised hosts and the disease is symptomatic and contagious .

Key Details

Gender

All

Age Range

16 Years - 60 Years

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2024-12-10

Completion Date

2025-06-01

Last Updated

2024-11-29

Healthy Volunteers

No

Conditions

Interventions

DIAGNOSTIC_TEST

P24 antigens and antibody

estimation of antigens and antibodies to diagnose HIV

DIAGNOSTIC_TEST

zeihl - Nelsen stain

staining sputum from patients with HIV to detect tubercle bacilli

DIAGNOSTIC_TEST

culture on Lowenstein jensen media

spenciem will be inoculated on LJ media and kept for 2-8 weeks, to see small white colonies

DIAGNOSTIC_TEST

Molecular detection of antibiotic resistance

to see the pattern of antibiotic resistance of tubercle bacilli

Locations (1)

Faculty of medicine

Sohag, Egypt