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The Effect of Preoperative Albumin Administration on Postoperative Acute Kidney Injury in Pediatric Patients With Hypoalbuminemia Undergoing Cardiac Surgery
Sponsor: Seoul National University Hospital
Summary
The study aims to evaluate whether preoperative albumin supplementation in pediatric patients with hypoalbuminemia undergoing cardiac surgery can reduce inflammatory responses and prevent acute kidney injury (AKI) following cardiopulmonary bypass.
Official title: The Effect of Preoperative Albumin Administration on Postoperative Acute Kidney Injury in Pediatric Patients With Hypoalbuminemia Undergoing Cardiac Surgery: A Prospective Randomized Clinical Trial
Key Details
Gender
All
Age Range
Any - 7 Years
Study Type
INTERVENTIONAL
Enrollment
190
Start Date
2025-01-09
Completion Date
2027-12-31
Last Updated
2025-04-23
Healthy Volunteers
No
Interventions
Albumin solution
A 20% albumin solution is administered over one hour starting from the induction of anesthesia, using the following formula: (4.0-preoperative serum albumin (g/dL))×plasma volume (kg×0.65-0.8 dL)
Crystalloid solutions
The same volume of crystalloid solution as the administered albumin is infused.
Locations (1)
Seoul National University Hospital
Seoul, Seoul, South Korea