Clinical Research Directory
Browse clinical research sites, groups, and studies.
Exploring the Minimum Effective Concentration and Volume of Ropivacaine for Sacral Plexus Anesthesia
Sponsor: Yilin Zhao
Summary
The goal of this clinical trial is to explore the minimum effective concentration and volume of ropivacaine for sacral plexus anesthesia. The main questions it aims to answer are: * The distribution of different volumes of ropivacaine after caudal anesthesia * The blockade level after caudal anesthesia with varying doses * The minimum effective concentration of ropivacaine among pediatric patients of different age groups Researchers will inject different doses or concentrations of ropivacaine into the caudal canal to observe the drug's spread range, the level of blockade, and the duration of its effect. Participants will: * Undergo magnetic resonance imaging (MRI) examinations before and after caudal anesthesia * Will be detected the blockade level after caudal anesthesia
Official title: Exploring the Minimum Effective Concentration and Volume of Ropivacaine for Sacral Plexus Anesthesia in Children of Different Ages
Key Details
Gender
All
Age Range
1 Day - 7 Years
Study Type
INTERVENTIONAL
Enrollment
180
Start Date
2024-05-10
Completion Date
2026-03-20
Last Updated
2024-12-02
Healthy Volunteers
No
Conditions
Interventions
Low-dose ropivacaine
0.5 ml/Kg ropivacaine
Medium-dose of ropivacaine
1ml/Kg ropivacaine
High-dose ropivacaine
1.5 ml/Kg ropivacaine
Locations (1)
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China