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ENROLLING BY INVITATION
NCT06711679
PHASE4

Exploring the Minimum Effective Concentration and Volume of Ropivacaine for Sacral Plexus Anesthesia

Sponsor: Yilin Zhao

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to explore the minimum effective concentration and volume of ropivacaine for sacral plexus anesthesia. The main questions it aims to answer are: * The distribution of different volumes of ropivacaine after caudal anesthesia * The blockade level after caudal anesthesia with varying doses * The minimum effective concentration of ropivacaine among pediatric patients of different age groups Researchers will inject different doses or concentrations of ropivacaine into the caudal canal to observe the drug's spread range, the level of blockade, and the duration of its effect. Participants will: * Undergo magnetic resonance imaging (MRI) examinations before and after caudal anesthesia * Will be detected the blockade level after caudal anesthesia

Official title: Exploring the Minimum Effective Concentration and Volume of Ropivacaine for Sacral Plexus Anesthesia in Children of Different Ages

Key Details

Gender

All

Age Range

1 Day - 7 Years

Study Type

INTERVENTIONAL

Enrollment

180

Start Date

2024-05-10

Completion Date

2026-03-20

Last Updated

2024-12-02

Healthy Volunteers

No

Conditions

Interventions

DRUG

Low-dose ropivacaine

0.5 ml/Kg ropivacaine

DRUG

Medium-dose of ropivacaine

1ml/Kg ropivacaine

DRUG

High-dose ropivacaine

1.5 ml/Kg ropivacaine

Locations (1)

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China