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NCT06713915

Diagnostic Performance of Contrast-Enhanced Mammography

Sponsor: ZHOU Yidong

View on ClinicalTrials.gov

Summary

Contrast-Enhanced Mammography (CEM) is a functional breast imaging technology. Like magnetic resonance imaging (MRI), CEM neovascularization enhancement can improve cancer detection rates, while lack of enhancement may lead to benign determination. The advantages of CEM are dramatically apparent in women with dense breasts. The purpose of this study was to investigate the additional diagnostic value of CEM added to the standard practice of mammography plus ultrasonography(US) in patients with suspicious breast lesions. This study was a single-center prospective-retrospective combined observational study. In the prospective part, women with suspected breast abnormalities undergo prospective CEM evaluation, including acquisition of low energy (LE) images and recombined images (RI) showing enhancement, concurrently with breast US. The retrospective part selected the mammography and breast US data of female patients with suspected breast abnormalities who had previous baseline matching.

Official title: Diagnostic Performance of Contrast-Enhanced Mammography in Suspicious Breast Lesions

Key Details

Gender

FEMALE

Age Range

30 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

600

Start Date

2025-01

Completion Date

2027-12

Last Updated

2024-12-03

Healthy Volunteers

No

Conditions

Interventions

DIAGNOSTIC_TEST

Contrast-Enhanced Mammography

Only patients in the prospective cohort will undergo CEM in addition to breast ultrasound.

Locations (1)

Department of Breast Surgery,Peking Union Medical College Hospital

Beijing, Beijing Municipality, China