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Impacts of Nitrogen Deposition in the Natural Environment on Pollen Allergy in Belgium
Sponsor: prof. dr. Rik Schrijvers
Summary
The investigators want to study the effect of environmental nitrogen enrichment on the allergy burden in pollen-sensitized subjects.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2022-06-29
Completion Date
2025-04
Last Updated
2024-12-03
Healthy Volunteers
Yes
Conditions
Interventions
Immunoreactivity testing
Blood samples will be collected and used to determine the intensity of the allergenicity of the subject toward different types of pollen. This will be done by the detection of sIgE antibodies to the pollen extracts and basophil activation testing (BAT) with pollen extracts.
Immunoreactivity testing (negative control)
Blood samples will be collected and used to determine the background activity of our immunoreactivity tests. The investigators will use samples from negative controls to demonstrate that non-allergic individuals do not react to our assays, confirming that our pollen extracts have no background reactivity. This will be done by the detection of sIgE antibodies to the pollen extracts and basophil activation testing (BAT) with pollen extracts.
Locations (1)
University Hospitals Leuven
Leuven, Vlaams-Brabant, Belgium