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A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Single Doses of Different Versions of Injectable CagriSema in Adults With Overweight or Obesity
Sponsor: Novo Nordisk A/S
Summary
This study will compare the blood levels of cagrilintide and semaglutide when the same dose is given in two different versions of CagriSema. CagriSema is a medicine that combines two medicines called cagrilintide and semaglutide. It is still being tested in studies and is not yet available for doctors to prescribe. Participants will get an injection with each of the two versions of CagriSema at two different times at the clinic. Like all medicines, the study medicine may have side effects. The study will last for about 18 weeks.
Official title: Comparing the Pharmacokinetics of Cagrilintide and Semaglutide Following Single Subcutaneous Doses of Different CagriSema Presentations, in a Crossover Manner in Adult Participants With Overweight or Obesity
Key Details
Gender
All
Age Range
18 Years - 64 Years
Study Type
INTERVENTIONAL
Enrollment
18
Start Date
2024-12-02
Completion Date
2025-03-28
Last Updated
2026-08-31
Healthy Volunteers
No
Conditions
Interventions
CagriSema (cagrilintide B and semaglutide I)
Cagrilintide and semaglutide will be administered subcutaneously using DV3384 pen-injector.
CagriSema A
Cagrilintide and semaglutide will be administered subcutaneously using PDS290 pen-injector.
Locations (1)
Celerion, Lincoln
Lincoln, Nebraska, United States