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COMPLETED
NCT06716307
PHASE1

A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Single Doses of Different Versions of Injectable CagriSema in Adults With Overweight or Obesity

Sponsor: Novo Nordisk A/S

View on ClinicalTrials.gov

Summary

This study will compare the blood levels of cagrilintide and semaglutide when the same dose is given in two different versions of CagriSema. CagriSema is a medicine that combines two medicines called cagrilintide and semaglutide. It is still being tested in studies and is not yet available for doctors to prescribe. Participants will get an injection with each of the two versions of CagriSema at two different times at the clinic. Like all medicines, the study medicine may have side effects. The study will last for about 18 weeks.

Official title: Comparing the Pharmacokinetics of Cagrilintide and Semaglutide Following Single Subcutaneous Doses of Different CagriSema Presentations, in a Crossover Manner in Adult Participants With Overweight or Obesity

Key Details

Gender

All

Age Range

18 Years - 64 Years

Study Type

INTERVENTIONAL

Enrollment

18

Start Date

2024-12-02

Completion Date

2025-03-28

Last Updated

2026-08-31

Healthy Volunteers

No

Conditions

Interventions

DRUG

CagriSema (cagrilintide B and semaglutide I)

Cagrilintide and semaglutide will be administered subcutaneously using DV3384 pen-injector.

DRUG

CagriSema A

Cagrilintide and semaglutide will be administered subcutaneously using PDS290 pen-injector.

Locations (1)

Celerion, Lincoln

Lincoln, Nebraska, United States