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Oral and Intravenous Methadone for Analgesia in Cardiac Surgery
Sponsor: Mayo Clinic
Summary
The purpose of this study is to compare the effects of administration of oral methadone preoperatively and intravenous methadone upon induction of general anesthesia on postoperative pain for patients undergoing elective cardiac surgery.
Official title: Comparison of Oral and Intravenous Methadone for Analgesia in Cardiac Surgery
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
41
Start Date
2025-04-14
Completion Date
2025-07-14
Last Updated
2026-08-06
Healthy Volunteers
No
Conditions
Interventions
Oral methadone, immediately prior to transport
Patients will receive 0.4mg/kg PO methadone immediately prior to transport to the operating room
Intravenous methadone
Patients will receive 0.3mg/kg IV methadone after induction of general anesthesia
Locations (1)
Mayo Clinic in Rochester
Rochester, Minnesota, United States