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Ultralong-segment Barrett's Esophagus: Towards a Capsule-sponge Surveillance Strategy
Sponsor: Erasmus Medical Center
Summary
The purpose of this study is to evaluate the Endosign capsule sponge test as a novel surveillance method in patients with an ultralong-segment Barrett's esophagus.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
137
Start Date
2025-02-03
Completion Date
2027-09
Last Updated
2025-08-12
Healthy Volunteers
No
Conditions
Interventions
EndoSign
The EndoSign cell collection device is a non-endoscopic capsule sponge device used to collect pan-esophageal samples. The Endosign procedure consists of an expandable, spherical mesh, which is attached to a string and contained within a soluble capsule. Seven minutes after swallowing (once the capsule has dissolved), the spherical mesh, which measures around 3cm in diameter is retrieved by pulling on the string. Upon retrieval the capsule-sponge scrapes against the surface of the top of the stomach and esophagus and collects epithelial cells. The capsule-sponge sample is then placed into a preservative fluid and the specimen is processed for molecular tests.
Locations (1)
Erasmus Medisch Centrum
Rotterdam, South Holland, Netherlands