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Evaluation of Long-Acting Injectable (LAI) and Teen Clubs in Adolescents (ATTUNE).
Sponsor: Africa Health Research Institute
Summary
This is a 2-stage study assessing the effect of peer navigation (support from peers) and long-acting injectable antiretroviral therapy (ART) on viral suppression and retention in care among adolescents living with HIV and receiving care in South Africa.
Key Details
Gender
All
Age Range
12 Years - 19 Years
Study Type
INTERVENTIONAL
Enrollment
720
Start Date
2026-02-09
Completion Date
2029-06-30
Last Updated
2026-04-03
Healthy Volunteers
Yes
Conditions
Interventions
Peer navigation effectiveness
To determine the effectiveness of peer navigation on viral suppression and retention in care among adolescents living with HIV in South Africa.
Locations (12)
Charlotte Maxeke Hospital
Johannesburg, Gauteng, South Africa
Rahima Moosa Mother and Child Hospital
Johannesburg, Gauteng, South Africa
Kgabo CHC
Pretoria, Gauteng, South Africa
KT Motubatse CHC
Pretoria, Gauteng, South Africa
Soshanguve Block JJ
Pretoria, Gauteng, South Africa
Soshanguve Block TT
Pretoria, Gauteng, South Africa
Cato Manor CHC
Durban, KwaZulu-Natal, South Africa
KwaMashu CHC
Durban, KwaZulu-Natal, South Africa
Mtubatuba CHC
Mtubatuba, KwaZulu-Natal, South Africa
Somkhele CHC
Mtubatuba, KwaZulu-Natal, South Africa
Eerste River Hospital
Cape Town, Western Cape, South Africa
Michael Mapongwana CHC
Cape Town, Western Cape, South Africa