Clinical Research Directory

Inclusion Criteria: * Adults aged 18 to 65 years, regardless of gender. * Patients scheduled for routine painless gastrointestinal endoscopy, including gastroscopy, colonoscopy, or both. * ASA physical status classification: I or II. * BMI between 18 kg/m² and 28 kg/m². * Anticipated procedural duration of no more than 30 minutes. * Patients who have provided written informed consent after understanding the study purpose, procedures, and potential risks. Exclusion Criteria: * History of psychiatric disorders such as schizophrenia, bipolar disorder, or personality disorders, or a history of alcohol, stimulant, or other substance abuse. * Known allergies or intolerance to any medication used in the study, including remimazolam, sufentanil, or benzodiazepines. * Patients requiring complex endoscopic procedures (e.g., ERCP, endoscopic submucosal dissection, endoscopic mucosal resection, or peroral endoscopic myotomy). * History of severe hepatic or renal disease. * Pregnant or lactating women. * Participation in another clinical study within the past three months. * Any condition or factor that, in the investigator's judgment, makes the patient unsuitable for participation in the study.