Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT06723561
PHASE2

Treating Central Neuropathic Pain With Low Dose Naltrexone for People With Spinal Cord Injury

Sponsor: Medical College of Wisconsin

View on ClinicalTrials.gov

Summary

The goal of this pilot clinical trial is to find out how well low dose naltrexone works for people with pain due to spinal cord injury. The main questions it aims to answer are: will low dose naltrexone reduce pain, and increase the quality of life for people with central neuropathic pain due to spinal cord injury. Hypothesis 1: LDN will decrease the severity of CNP in adult patients with SCI as measured by the Neuropathic Pain Scale (NPS) Hypothesis 2: LDN will improve quality of life of patients with SCI as measured by various validated clinical tools There is no comparison group. This study is being completed to give investigators more information for how to best run a larger clinical trial. Participants will be asked to take an oral dose of 4.5mg of naltrexone, daily, for 12 weeks.

Official title: Low Dose Naltrexone in the Treatment of Central Neuropathic Pain After Traumatic Spinal Cord Injury: A Pilot Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

10

Start Date

2025-02-01

Completion Date

2026-12-31

Last Updated

2025-10-21

Healthy Volunteers

No

Interventions

DRUG

4.5mg daily dose of naltrexone

Study subjects will take a daily 4.5mg dose of naltrexone.

Locations (1)

Medical College of Wisconsin

Milwaukee, Wisconsin, United States