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Effects of Vitamin C on Shock Duration and Microcirculation in Patients With Vasoplegia Syndrome After Cardiac Surgery
Sponsor: Southeast University, China
Summary
This pilot study intends to observe the effect of intravenous vitamin C on the prognosis and sublingual microcirculation in patients with vasoplegia syndrome after cardiac surgery through a prospective randomized controlled study method.
Official title: Clinical Study of the Effect of Intravenous Vitamin C on the Prognosis and Sublingual Microcirculation in Patients With Vasoplegia Syndrome After Cardiac Surgery.
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2024-07-01
Completion Date
2026-08-31
Last Updated
2026-09-16
Healthy Volunteers
No
Conditions
Interventions
Vit C
Patients in the vitamin C group received standard care (fluid resuscitation, norepinephrine infusion to maintain MAP \>65 mmHg, additional vasopressors and hydrocortisone as judged by the attending clinicians) plus intravenous vitamin C (1.5g of vitamin C injection in 100 mL normal saline) over 30 minutes, repeated every 6 hours for a total of 4 doses.
Standard Preparation
Patients in the control group received standard care.
Locations (1)
Zhongda Hospital Southeast University
Nanjing, Jiangsu, China