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Tapering Heart Failure Medication in Patients With Heart Failure With Recovered Ejection Fraction; Open Label Prospective Random Trial
Sponsor: Chungnam National University Hospital
Summary
Study start date is on Nov 27th 2024. A patient with an initial ejection fraction (EF) of less than 40%, whose follow-up shows an improvement to an EF of 50% or higher, along with the left ventricular end-diastolic diameter returning to the normal range and taking 3 more heart failure medication randomed to drug tapering group ( RAS blocker or beta blocker) or continuing medication group.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2025-03-06
Completion Date
2027-11-26
Last Updated
2026-03-27
Healthy Volunteers
No
Interventions
RAS blocker tapering group
RAS blocker tapering out
Beta blocker tapering out
Beta blocker tapering out group
Locations (2)
Jeonbuk national university hospital
Jeonju, Jeollabuk-do, South Korea
Chungnam national university hospital
Daejeon, Republic of Korea, South Korea