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Assessment of Nebulized Tranexamic Acid in Functional Endoscopic Sinus Surgery Using Modena Bleeding Score
Sponsor: Assiut University
Summary
The aim of this study is to investigate the effect of preoperative administration of intravenous or nebulized tranexamic acid on surgical field, blood loss, anesthetic consumption and hemodynamics of patients undergoing FESS. Primary outcome Modena Bleeding Score (MBS) assessing surgical field Secondary outcome 1. Patient hemodynamics. 2. Anesthetic consumption, Extra doses of fentanyl and propofol and sevoflurane\>2 3. Postoperative complications: including any adverse effects to TXA e.g.nausea, vomiting, any visual disturbances, fits, and any thrombotic manifestation.
Official title: Assessment of Nebulized Tranexamic Acid in Functional Endoscopic Sinus Surgery Using Modena Bleeding Score. A Randomized Double Blinded Controlled Trial.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2025-01-29
Completion Date
2026-01-01
Last Updated
2025-01-29
Healthy Volunteers
Yes
Conditions
Interventions
Tranexamic Acid (TXA)
To see if nebulised TXA is better to control blood loss in functional Endoscopic sinus surgery
Tranexamic Acid
To see if intravenous TXA is better to control blood loss in functional Endoscopic sinus surgery
Locations (1)
Main building, Assiut University Hospitals
Asyut, Egypt