Clinical Research Directory
Browse clinical research sites, groups, and studies.
Effects of Dextrose Versus Saline Infusion on Intrathecal Morphine-Induced Postoperative Nausea and Vomiting During Gynecological Abdominal Surgeries: Randomized Controlled Double-blind Study
Sponsor: Assiut University
Summary
Neuraxial anesthesia, which includes epidural anesthesia and intrathecal anesthesia, is a frequent anesthetic approach for cesarean delivery and other lower abdominal and lower limb anesthetic procedures. Neuraxial morphine (intrathecal or epidural administration) provides high-quality analgesia after gynecological abdominal surgeries. the aim of the study is to compare the effects of intraoperative infusion of dextrose 5 % and 10 % versus normal saline 0.9 % on the incidence of intrathecal morphine-induced postoperative nausea and vomiting (PONV) in women undergoing gynecological abdominal surgeries. (Neuraxial anesthesia).
Key Details
Gender
All
Age Range
20 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
63
Start Date
2025-01-01
Completion Date
2026-02-01
Last Updated
2024-12-10
Healthy Volunteers
No
Conditions
Interventions
dextrose 5%
patients will receive 5 % dextrose infusion
Dextrose 10%
patients will receive 10 % dextrose infusion (25gm/ 250 mL)
0.9% saline
patients will receive infused IV 0.9 % saline