Clinical Research Directory

Inclusion Criteria: From December 2024 to May 2025, preterm infants (gestational age \<37 weeks) or low birth weight infants (birth weight \<2500 g) who receive their first ROP screening at Xinhua Hospital or partner institutions will be included. Exclusion Criteria: 1. Death before the first screening; 2. Death or loss to follow-up before complete retinal vascularization; 3. Presence of other diseases causing incomplete retinal vascularization, such as familial exudative vitreoretinopathy, incontinentia pigmenti, or Coats disease; 4. Coexisting conditions affecting the classification or staging of ROP, such as corneal opacity, congenital cataract, persistent fetal vasculature, retinoblastoma, anophthalmia, Terson syndrome, or other ocular infections or diseases; 5. Poor systemic condition preventing fundus examination; 6. History of ocular trauma or surgery (excluding treatments for ROP); 7. Poor-quality fundus images; 8. Other conditions deemed exclusionary by the investigators.