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RECRUITING
NCT06733376
NA

Evaluating Evidenced Based Options for PTSD Treatment

Sponsor: Rush University Medical Center

View on ClinicalTrials.gov

Summary

This study will look at: How practical it is to offer another round of proven therapy. How effective different therapy options are for people who didn't respond to the first treatment. The goal is to improve personalized care by: Identifying factors that might predict how someone will respond to a second treatment. Creating a simple tool to spot people who might not respond to treatment early, so they can start a different option sooner. The findings will help improve PTSD care by offering better follow-up treatments and matching patients with the approach that works best for them.

Official title: Evaluating Evidence Based Options for Initial PTSD Treatment Non-Responders

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

400

Start Date

2025-10-06

Completion Date

2030-06-01

Last Updated

2025-10-22

Healthy Volunteers

No

Interventions

BEHAVIORAL

Cognitive Processing Therapy

Cognitive Processing Therapy is a first-line intervention for the treatment of PTSD that focuses on changing unhelpful patterns of thinking.

BEHAVIORAL

Prolonged Exposure

Prolonged Exposure is an evidence-based treatment for PTSD that helps to reduce the intensity of distress by gradually exposing participants to trauma-related memories, feelings, and situations in real life.

BEHAVIORAL

Skills Training for Affective and Interpersonal Regulation

Skills Training for Affective and Interpersonal Regulation (STAIR) is a evidence-based treatment geared towards helping regulate emotional and interpersonal needs of those with PTSD.

Locations (1)

Rush University Medical Center

Chicago, Illinois, United States