Clinical Research Directory

Inclusion Criteria: * Age ≥ 18 years, there is no upper age limit * Diagnosed with heart failure regardless of left ventricular ejection fraction * Having New York Heart Association (NYHA) Class III/IV irrespective of prior hospitalisation for heart failure, or NYHA II with a history of at least one hospitalisation for heart failure within the previous 12 months * Elevated N-terminal pro-B-type natriuretic peptide (NT-proBNP) within 12 months: (a) ≥450 pg/ml for patients under 50 years; (b) ≥900 pg/ml for patients aged 50-75 years; (c) ≥1800 pg/ml for patients over 75 years. Exclusion Criteria: * NYHA I * Life expectancy \<6 months * Physical characteristics that prevented use of the ReDS (body mass index \< 22 or \>39, and height less than 155 cm or higher than 195 cm) * Implantation of a left ventricular assist device or cardiac transplantation.