Clinical Research Directory

Inclusion Criteria: 1. Diagnosis of severe β -thalassemia 2. Age between 7-10 years old, male and female; Weight \< 40kg 3. The patient has or does not have an HLA-compatible or semi-compatible donor, but unconditional transplantation or refusal of blood stem cell transplantation; Patients with thalassemia gene therapy without conditions or refusal; 4. There are fully compatible or incompatible HLA donors, and the physical examination meets the donor conditions; 5. The patient and family members agree to receive hypertransplant therapy and sign a written informed consent prior to the transplant trial. Exclusion Criteria: 1. Mental patients; 2. Participants in other drug clinical trials within the past 1 month; 3. There are no suitable HLA-incompatible donors. 4. Other researchers decide that it is not suitable to participate in this researcher.