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Changes in Salivary Asprosin, IL-39, IL-40 and IL-1β Levels in Diabetic Patients with Periodontitis
Sponsor: Necmettin Erbakan University
Summary
The aim of this study is to determine the relationships between asprosin, IL-39, IL-40 and IL-1β in saliva between individuals with and without diabetes and between individuals with periodontitis and healthy individuals and to determine the potential roles of these biomarkers that are multiplied in periodontal disease. The study aims to evaluate whether these biomarkers can be used for periodontal diagnosis or prognosis. The questions answered by the study are as follows: Do asprosin, IL-39, IL-40 and IL-1β biomarker levels differ between individuals with and without diabetes? Do these biomarker levels differ significantly between individuals with periodontitis and individuals who are healthy? Can these biomarkers be used in the early diagnosis or recording the progression of periodontal diseases?
Official title: Evaluation of Salivary Asprosin, IL-39,IL-40 and IL-1β Levels in Diabetic Patients with Periodontitis
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
176
Start Date
2025-01-10
Completion Date
2025-02-20
Last Updated
2024-12-16
Healthy Volunteers
Yes
Interventions
Periodontal examination and saliva collection
Before the periodontal examination, saliva samples are collected from each patient participating in the study and periodontal measurements are made.
Locations (1)
Necmettin Erbakan University
Konya, Meram, Turkey (Türkiye)