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Alternative Diagnoses in Patients About to Start Empiric Tuberculosis Treatment
Sponsor: Stichting Longartsen voor Afrika
Summary
This study is being conducted to determine whether in patients who are diagnosed with tuberculosis on a clinical basis (where tuberculosis is not found in the sputum) might have other lung diseases than tuberculosis. Depending on the precise nature of your complaints, additional investigations shall be requested by the study investigators. Possible additional investigations will include laboratory tests on samples of your blood, an additional chest X-ray, lung function testing (where you will have to blow air into a machine, so that your lung capacity is registered), CT-scan, and bronchoscopy. The information obtained through the investigations done in this study will help in the management of your illness and other patients who are diagnosed with tuberculosis on a clinical basis.
Official title: Enhanced Diagnostic Workup for Patients About to Start Empiric Tuberculosis Treatment in Lusaka, Zambia
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2024-12-01
Completion Date
2026-01-30
Last Updated
2025-07-14
Healthy Volunteers
No
Conditions
Interventions
Enhanced diagnostic workup
Patients will undergo review by a study physician, including a detailed history and physical examination, as well as review of additional investigations that have been performed thus far. Based on the precise nature of the complaints, and additional findings, additional diagnostic testing may be requested, including, but not limited to: blood testing, spirometry, computed tomography of the chest, repeat chest X-ray, sputum investigations, or bronchoscopy.
Locations (1)
University Teaching Hospital
Lusaka, Zambia