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The Impact of a 48-hour Fast with or Without Exercise on Immune Cell Metabolism and Glycemic Control in Healthy Active Adults
Sponsor: University of British Columbia
Summary
Many individuals engage in fasting for its purported health benefits but the effects of fasting on immune cell and whole body metabolism are not well understood in humans. Moreover, how exercising during a prolonged fast impacts immunometabolic outcomes is unclear. This study will determine how a 2 day fast - performed with or without daily exercise - impacts immune cell bioenergetics, immune cell function, and whole-body glycemic control in healthy active individuals.
Official title: The Impact of a 48-hour Fast with or Without Exercise on Immune Cell Function, Bioenergetics, and Glycemic Control in Healthy Active Adults: a Randomized Crossover Trial
Key Details
Gender
All
Age Range
19 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
15
Start Date
2025-01-10
Completion Date
2025-08-01
Last Updated
2025-03-07
Healthy Volunteers
Yes
Conditions
Interventions
Fasting + Exercise (FAST+EX): fasting + exercise condition
Participants will complete a 48-hour fast. One hour of exercise will be performed on each morning of the fast.
Fasting only (FAST): Non-exercise fasting condition
Participant will complete a 48-hour fast. No structured exercise will be performed during each of the fasting days.
Locations (1)
University of British Columbia Okanagan Campus
Kelowna, British Columbia, Canada