Clinical Research Directory

Inclusion Criteria: * Women over 50 years old * Women with a clinical diagnosis of genuine or mixed stress urinary incontinence (SUI) with at least 6 months of evolution. Using the definitions of urinary incontinence internationally accepted by the ICS (International Continence Society): to. SUI: any involuntary loss of urine, immediately preceded by exertion. b. Mixed UI: any involuntary loss of urine, immediately preceded by exertion or an uncontrollable desire to urinate. The predominance of effort will be assessed when more than 50% of the patient's daily losses occur preceded by effort. * Women in whom rehabilitative treatment has failed or patients who refuse to undergo rehabilitative or surgical treatment * Patients without active urinary tract infection (negative urine culture) at the time of recruitment and treatment * Signing of the informed consent form Exclusion Criteria: * Patients with a medical history of previous surgery for incontinence, prolapse or urological/gynecological/colorectal surgery * Major surgery or serious trauma of the subject in the previous semester * Women with mixed urinary incontinence, with predominant symptoms of urgency * History of high-pressure detrusor overactivity * Present infravesical obstruction, vesico-ureteral reflux or clinical history of urinary fistula (it will be ruled out depending on the case by urethrocystoscopy, urethrocystography and flowmetry). * Present any malignant neoplasm, unless it is basal cell or squamous cell carcinoma of the skin, or present a history of malignant tumors, unless they have been in remission during the previous 5 years. * Cardiopulmonary disease that, in the opinion of the investigator, is unstable or serious enough to exclude the patient from the study. * Medical or psychiatric illness of any type that, in the opinion of the researcher, may be a reason for exclusion from the study. * History of alcohol or other addictive substance abuse in the 6 months prior to inclusion * Subject's allergy to anesthetics