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Systemic Treatment Options for Generalized Lichen Planus
Sponsor: Sheikh Zayed Medical College
Summary
Lichen planus is a chronic inflammatory skin condition with unknown etiology. It requires a long term treatment. Evaulating the most efficacious, safe and affordable treatment option is the need of the hour. This study is going to compare the efficacy of two familiar drugs (acitretin and methotrexate) in the treatment of generalized lichen planus as to find out the relatively more effective and safer treatment.
Official title: Comparison of Efficacy of Oral Methotrexate and Acitretin for Generalized Lichen Planus
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
124
Start Date
2024-12-10
Completion Date
2025-03-20
Last Updated
2024-12-18
Healthy Volunteers
No
Conditions
Interventions
Methotrexate (drug)
oral methotrexate 10 mg per week for 12 weeks
Acitretin
oral acitretin 50 mg once daily for 12 weeks
Locations (1)
Sheikh zayed Medical College and Hospital
Rahim Yar Khan, Punjab Province, Pakistan