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Recompensation in Alcohol Related Hepatitis
Sponsor: Nina Kimer
Summary
Genetic activity and metabolic changes may be part of the pathogenesis in alcohol related hepatitis. We do not know exactly how alcohol cessation affects liver functions and metabolism. The aim of this study is to assess the impact of alcohol cessation in patients with alcohol related hepatitis and gain knowledge of the metabolic and genetic functions of the liver during remission and recompensation from alcohol related hepatitis. The study will assess 1. The effect of alcohol cessation on the liver. 2. The biological mechanisms involved in healing after alvohol-cessation 3. The effect of motivational enhcament therapy in alcohol cessation after alcohol related hepatitis. 4. The metabolic changes of lipids and proteins in the liver Participants are offered motivational enhancement therapy and standard of care.
Official title: Recompensation in Alcohol Related Hepatitis- A Prospective Cohort With Alcohol Cessation
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
160
Start Date
2024-11-25
Completion Date
2029-12-31
Last Updated
2025-02-27
Healthy Volunteers
No
Conditions
Interventions
Motivational enhancement therapy
The intervention consists of three motivational interviews with the focus to enhance the participants motivation to enter treatment of alcohol use disorder. the interviews are structured and based on the model Motivational enhancement therapy.
Locations (1)
University Hospital Hvidovre
Hvidovre, Denmark