Clinical Research Directory
Browse clinical research sites, groups, and studies.
Risk Factors for Complications After Cranioplasty
Sponsor: Qilu Hospital of Shandong University
Summary
Cranial defects often result from brain injuries, hemorrhages, strokes, or brain tumors. These conditions can increase pressure inside the skull, and if left untreated, may lead to dangerous complications like brain herniation. To manage this, a common procedure called decompressive craniectomy is performed to reduce intracranial pressure. While this surgery often stabilizes the patient's condition, it leaves a cranial defect that exposes the brain to external risks, including pressure fluctuations and potential damage. In severe cases, patients with larger defects may develop complications such as sinking skin flap syndrome. Cranial reconstruction, also known as cranioplasty, is an important procedure to restore the skull's structure and protect the brain. This surgery can improve brain function, stabilize intracranial pressure, and enhance the patient's appearance. While cranioplasty is a standard neurosurgical procedure, it has a relatively high risk of complications compared to other brain surgeries. Common complications include infections, bleeding, hydrocephalus, and seizures. In severe cases, complications may lead to the failure of the reconstruction. Understanding the factors that contribute to complications after cranioplasty is crucial for neurosurgeons to improve outcomes and reduce risks. This study aims to identify these factors and develop predictive models for postoperative complications of cranioplasty.
Official title: A Retrospective Study to Identify Risk Factors for Complications After Cranioplasty
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
1000
Start Date
2024-12-17
Completion Date
2025-12-31
Last Updated
2025-06-05
Healthy Volunteers
No
Locations (3)
Department of Neurosurgery, Daping Hospital of Army Medical University
Chongqing, Chongqing Municipality, China
Department of Neurosurgery, Tang-Du Hospital
Xi'an, Shaanxi, China
Department of Neurosurgery, Qilu Hospital of Shandong University
Jinan, Shandong, China