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RECRUITING
NCT06740773

Risk Factors for Complications After Cranioplasty

Sponsor: Qilu Hospital of Shandong University

View on ClinicalTrials.gov

Summary

Cranial defects often result from brain injuries, hemorrhages, strokes, or brain tumors. These conditions can increase pressure inside the skull, and if left untreated, may lead to dangerous complications like brain herniation. To manage this, a common procedure called decompressive craniectomy is performed to reduce intracranial pressure. While this surgery often stabilizes the patient's condition, it leaves a cranial defect that exposes the brain to external risks, including pressure fluctuations and potential damage. In severe cases, patients with larger defects may develop complications such as sinking skin flap syndrome. Cranial reconstruction, also known as cranioplasty, is an important procedure to restore the skull's structure and protect the brain. This surgery can improve brain function, stabilize intracranial pressure, and enhance the patient's appearance. While cranioplasty is a standard neurosurgical procedure, it has a relatively high risk of complications compared to other brain surgeries. Common complications include infections, bleeding, hydrocephalus, and seizures. In severe cases, complications may lead to the failure of the reconstruction. Understanding the factors that contribute to complications after cranioplasty is crucial for neurosurgeons to improve outcomes and reduce risks. This study aims to identify these factors and develop predictive models for postoperative complications of cranioplasty.

Official title: A Retrospective Study to Identify Risk Factors for Complications After Cranioplasty

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

1000

Start Date

2024-12-17

Completion Date

2025-12-31

Last Updated

2025-06-05

Healthy Volunteers

No

Locations (3)

Department of Neurosurgery, Daping Hospital of Army Medical University

Chongqing, Chongqing Municipality, China

Department of Neurosurgery, Tang-Du Hospital

Xi'an, Shaanxi, China

Department of Neurosurgery, Qilu Hospital of Shandong University

Jinan, Shandong, China