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ENROLLING BY INVITATION
NCT06741917
PHASE4

Retrograde Intrarenal Surgery Low Risk Trial

Sponsor: National Taiwan University Hospital

View on ClinicalTrials.gov

Summary

In the treatment of kidney stones and upper ureteral stones, flexible ureteroscopic lithotripsy has become the mainstream choice due to its minimally invasive nature and high safety. However, there is still no universal consensus on the use of prophylactic antibiotics before surgery. Taiwan, located in the subtropical region, is one of the areas in the world with a high incidence of urinary tract stones. Currently, there are no established guidelines for the use of prophylactic antibiotics before flexible ureteroscopic lithotripsy in Taiwan. This study aims to evaluate the differences between single-dose, different types of prophylactic antibiotics in generally healthy adult patients undergoing flexible ureteroscopic lithotripsy.

Official title: Comparison of the Post-operative Infection by Using Different Type Prophylactic Antibiotics in Low Risk Patients Who Underwent Retrograde Intrarenal Surgery

Key Details

Gender

All

Age Range

20 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

200

Start Date

2024-12-04

Completion Date

2026-06-30

Last Updated

2024-12-19

Healthy Volunteers

No

Interventions

DRUG

Levofloxacin

single dose of oral Levofloxacin (500mg/tab) before retrograde intrarenal surgery

DRUG

Cefmetazole (drug)

single dose of intravenous Cefmetazole (1000 mg)before retrograde intrarenal surgery

Locations (1)

National Taiwan University Hospital

Taipei, Taiwan