Clinical Research Directory

Patients Inclusion Criteria: * 1\) 18-45 years; 2) Diagnosis within schizophrenia spectrum or affective disorders (i.e. F2.x or F3.x according to ICD-10 classification); 3) current antipsychotic treatment for more than one month on a regular daily dose and 4) Able to give informed consent. Exclusion Criteria: * 1\) Clinical or laboratory evidence of uncompensated medical disease; 2) Unstable psychiatric disorder; 3) Acute suicidal risk; 4) Planned hospitalization within the study period. Healthy controls Inclusion Criteria: * 1\) 18-45 years; 2) No psychiatric diagnosis or having first-degree relatives with psychiatric diagnoses; 3) able to give informed consent. Exclusion Criteria: * 1\) Clinical or laboratory evidence of uncompensated medical disease; 2) Indication of psychiatric disorder.