Clinical Research Directory

Inclusion Criteria: * Uncomplicated acute myocardial infarction (NSTEMI and STEMI) diagnosed according to the 2023 acute coronary syndrome guidelines of the ESC * Age ≥ 18 years at time of consent * Invasive management strategy and in case of PCI successful intervention of the culprit lesion defined by post-interventional TIMI 3 flow * Ability to understand and willingness to sign and date written informed consent Exclusion Criteria: * Myocardial infarction complicated by cardiac arrest (out-of-hospital cardiac arrest/in-hospital cardiac arrest) * PCI-related complications (coronary perforation, side branch closure, inability to deliver stent/balloon, aortic dissection, allergic reaction grade ≥2, stroke/thromboembolism, access site complications including pseudoaneurysm, arteriovenous fistula, retroperitoneal hemorrhage and arterial dissection/occlusion or emboli) * Malignant arrhythmias including sustained ventricular arrhythmias and persistent bradycardia (\< 50 beats per minute due to sinus node or atrioventricular conduction system abnormalities, second- /third-degree atrioventricular block) after PCI * Ongoing hemodynamic instability (systolic blood pressure \<90 mmHg, elevated lactate concentrations, need for inotropes or vasopressors) * Ongoing respiratory instability defined by Killip class \>I (rales, pulmonary edema) * Ongoing quantitative disorders of consciousness (somnolence, sopor, coma) * Acute kidney injury defined by Kidney Disease Improving Global Outcomes (KDIGO) stages 2 and 3 * Pregnancy * Untreated critical non-culprit lesions requiring revascularization during index hospitalization not allowing fast discharge * Immobility/limited mobility or social circumstances that prevent fast discharge assessed by an interprofessional care team