Clinical Research Directory
Browse clinical research sites, groups, and studies.
Clinical Decision Support to Identify Pediatric Patients With Undiagnosed Genetic Disease
Sponsor: Vanderbilt University Medical Center
Summary
This study will evaluate the effectiveness of SIGHT as a clinical support system to prompt provider/patient discussion and shared decision making regarding the need for genetic testing in the form of a chromosomal microarray. Identifying patients at high predicted probability of needing a test in clinical settings will be examined to determine if it decreases the duration of time to testing and increases diagnostic yield. SIGHT requires only data already collected in routine clinical encounters and is calculated prior to a clinical visit at VUMC.
Official title: Randomized Controlled Trial to Assess EHR Prediction Model to Identify Pediatric Patients With Undiagnosed Genetic Disease"
Key Details
Gender
All
Age Range
1 Year - 20 Years
Study Type
INTERVENTIONAL
Enrollment
1000
Start Date
2025-03-12
Completion Date
2027-02-01
Last Updated
2025-09-24
Healthy Volunteers
No
Interventions
SIGHT Prompted Provider Message
Among patients surpassing a 0.30 probability threshold that have a scheduled visit to pediatric primary care at VUMC, 500 will be randomized to the intervention and a SIGHT-prompted provider message will be generated.
Locations (1)
Vanderbilt University Medical
Nashville, Tennessee, United States