Clinical Research Directory

Inclusion Criteria: 1. Patients diagnosed with erosive hand OA, non-erosive hand OA, or first carpometacarpal joint OA with a Kellgren- Lawrence grade \>1 as determined by radiographic assessments and the American College of Rheumatology (ACR) classification 2. Patients age 40-75 3. Patients who are willing and able to adhere to follow-up schedule and protocol guidelines. 4. Patients who are willing and able to sign corresponding research subject consent form. Exclusion Criteria: 1. Patient has a history of neurological conditions, including multiple sclerosis or Parkinson's disease 2. Patient has had prior surgical treatment of the hands in the last 5 years or injection treatment in the last 6 months 3. Patient has secondary OA including causes such as gout, rheumatoid arthritis, psoriatic arthritis 4. Patient has used topical creams or gels for arthritic pain including nonsteroidal anti-inflammatory drugs, capsaicin, lidocaine, or counterirritants in the last 1 week 5. Patient has a history of carpal tunnel syndrome, cubital tunnel syndrome, or radial tunnel syndrome 6. Patient has a history of peripheral neuropathy 7. Patient has chronic pain conditions unrelated to hand condition 8. Patient has auto-immune or auto-inflammatory diseases 9. Patient has used tobacco within the last 90 days 10. Patient is not within the ages of 40-75 11. Patient has an active infection (local or systemic) 12. Patient is unwilling or unable to sign the corresponding research subject consent form 13. Patient meets any other criteria or has any other condition that, in the opinion of the investigator, would prevent them from completing the study or that, in the opinion of the investigator, would confound study results. \- Exclusion Criteria: \-