Clinical Research Directory

Inclusion Criteria: 1. Healthy patients aged ≥18 years 2. Full mouth bleeding and full mouth plaque index lower than or equal to 25% 3. Bone height for at least 10 mm long implants 4. Bone width of at least 5 mm and 6 mm for narrow (NP 3.75/3.5 mm) and regular (RP 4.3 mm) implants, respectively 5. Fresh extraction sockets with an intact buccal wall 6. At least 4 and 5 mm of bone beyond the root apex in the mandible and maxilla 7. Minimal insertion torque of 45 Ncm Exclusion Criteria: 1. General medical (American Society of Anesthesiologists, ASA, class III or IV) and/or psychiatric contraindications 2. Pregnancy and/or breastfeeding 3. Any interfering medication such as steroid therapy or bisphosphonate therapy 4. Alcohol and/or drug abuse 5. Heavy smoking (\>10 cigarettes/day) 6. Radiation therapy to head or neck region within 5 years 7. Untreated periodontitis 8. Acute and chronic infections of the adjacent tissues or natural dentition 9. Severe maxillomandibular skeletal discrepancy 10. High and moderate parafunctional activity 11. Absence of opposite teeth